Proton Pump Inhibitors Tied to Anemia, Other Health Issues in Heart Disease Patients

Published on September 28, 2016 by Sandy Liebhard

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A recent study confirms that proton pump inhibitors may not be as safe as generally perceived. According to a report published online in the International Journal of Cardiology this past June, the popular heartburn drugs may be linked to anemia, weight loss, and worsening metabolism in heart disease patients.

The study involved 604 heart treatment patients who were scheduled for cardiac rehab two to six months after their treatment. Of those, 294 were using Nexium or another proton pump inhibitor. Patients who had been diagnosed with atrial fibrillation were more likely to be taking the drugs, while those who had suffered a recent heart attack or who were obese were less likely.

The analysis revealed that patients taking proton pump inhibitors were six-times more likely to suffer from anemia. They also had a worsening metabolic profile, which could have been the result of less frequent use of ACE inhibitors or statins.

“High proportion of cardiovascular, particularly surgical patients with ischemic and valvelar heart disease utilized proton pump inhibitor[s] in prolonged courses,” the study’s authors concluded. “Prolonged courses of PPIs were connected with existence and worsening of red blood count indexes, older age, lesser weight of patients and underutilization of cardioprotective drugs.”

Proton Pump Inhibitor Side Effects and Lawsuits

Proton pump inhibitors like Nexium, Prilosec and PrevAcid are used by millions of people to treat GERD and other peptic disorders. Because these drugs are so ubiquitous, many people do not realize that they have been linked to a number of serious side effects, including certain bone fractures, magnesium and B12 deficiencies, and a type of drug-induced kidney inflammation called acute interstitial nephritis. Recent studies have also suggested that proton pump inhibitors may increase a patient’s risk for kidney problems, dementia and heart attacks.

A growing number of Nexium lawsuits and legal cases involving other proton pump inhibitors have been filed in U.S. courts on behalf of individuals who allegedly suffered serious kidney complications due to their use of the medications. The litigation was prompted by the publication of studies suggesting that the long-term use of proton pump inhibitors was associated with an increased risk of acute kidney injury, chronic kidney disease and renal failure.

Bernstein Liebhard LLP is representing individuals who may have been harmed by Nexium, Prilosec, PrevAcid or any other prescription or over-the-counter proton pump inhibitor. To discuss filing your own case with a member of our legal team, please call (888) 994-8177.

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