Proton Pump Inhibitor Kidney Failure

Published on August 23, 2016 by Sandy Liebhard

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Proton Pump Inhibitor Kidney Failure
Recent studies suggest that patients who use proton pump inhibitors like Nexium, Prilosec or PrevAcid may be more likely to experience kidney failure and other renal complications. Since their publication, a growing number of lawsuits have been filed that claim the manufacturers of these popular heartburn drugs failed to provide doctors and patients with adequate warnings regarding possible risks. Claimants seek financial compensation for their injury-related damages, including medical bills for dialysis and other treatments, lost wages, emotional distress, and pain and suffering.

Bernstein Liebhard LLP is now offering free legal reviews to kidney failure victims who suspect that treatment with a proton pump inhibitor may have contributed to their illness. If you would like to discuss filing a case of your own, please contact our office by calling .

Study Links Proton Pump Inhibitors to Renal Failure

Proton pump inhibitors are indicated to treat GERD and other disorders associated with excess stomach acid. They are available in both prescription and over-the-counter versions, and are taken by millions of people. While they are generally considered safe for short-term use, some research suggests that proton pump inhibitors are overused, with many patients taking the drugs for longer periods of time than what is generally recommended.

In April 2016, a study published in the Journal of the American Society of Nephrology suggested that proton pump inhibitors may pose a significant risk to the kidneys. The authors of the report analyzed patient records from national Veterans Administration databases, comparing 20,270 people who had recently started taking proton pump inhibitors to 173,321 people who had started taking H2 blockers. None of the study subjects had pre-existing kidney issues, and all were followed for five years.

The analysis revealed that:

  • Patients taking proton pump inhibitors were 32% more likely to experience a decline in kidney function compared to those taking H2 blockers.
  • Proton pump inhibitors were associated with a 28% increased risk for new cases of chronic kidney disease.
  • Patients taking proton pump inhibitors were 96% more likely to experience kidney failure compared to those using the other medications.
  • Kidney risks associated with proton pump inhibitors increased with duration of use, leveling off after about two years.

This study was not the first to suggest that proton pump inhibitors might harm the kidneys. In January 2016, research published in JAMA Internal Medicine suggested a 20 to 50% increased risk of chronic kidney disease in patients who used proton pump inhibitors. And in April 2015, a report appearing in CMAJ Open suggested that older people treated with proton pump inhibitors were more likely to experience an acute kidney injury, or the abrupt loss of kidney function.

Legal Help is Available

The attorneys at Bernstein Liebhard LLP are available now to review potential legal claims involving proton pump inhibitors and kidney failure. To contact our staff and arrange for your free lawsuit consultation, please call .

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