Did you recently view a Nexium, Prilosec or Prevacid lawsuit TV commercial? These advertisements have begun airing across the country, following the publication of several studies that suggest the use of heart burn drugs called proton pump inhibitors, or PPIs, may increase a patient’s risk for chronic kidney disease, renal failure, and other kidney complications.
Bernstein Liebhard LLP is investigating the kidney side effects that may be associated with proton pump inhibitors. If you recently saw a TV commercial advertising legal assistance for a Nexium, Prilosec or Prevacid lawsuit, and believe you might have a case, please call our office at . A member of our legal staff will evaluate your claim at no cost or obligation to you, and take the time to answer any questions you might have.
In 2014, some 14 million Americans used proton pump inhibitors like Nexium, Prilosec or Prevacid to treat indigestion, peptic ulcers, acid reflux and other gastric ailments. As a class, the drugs rank among the top-10 most prescribed medications in the U.S. They are also sold over-the-counter.
Prescription proton pump inhibitors include:
A number of over-the-counter versions are also available, including Nexium 24HR, Prilosec OTC, and Prevacid 24HR.
Proton pump inhibitors work by turning off pumps in the stomach that produce gastric acid. They are intended for short-term use, and should be taken at the lowest dose for the shortest duration possible to appropriately treat a specific condition.
Because they are so-widely used, most people believe that proton pump inhibitors are completely safe. However, these heart burn drugs have been tied to a number of serious side effects, especially when used over a long period of time. These complications include:
Drugs like Nexium, Prilosec and Prevacid have also been linked to serious kidney complications. In 2014, the U.S. Food & Drug Administration (FDA) ordered the manufacturers of all prescription proton pump inhibitors to add information to their product labels regarding acute interstitial nephritis, a serious inflammation of the kidneys that can lead to chronic kidney disease, and ultimately kidney failure. The labeling for OTC proton pump inhibitors does not include this information.
In 2016, two studies raised serious concerns about the potential for proton pump inhibitors to damage the kidneys. The first, which appeared in JAMA Internal Medicine in January, drew data from the medical records of more than 10,000 patients treated in community-based settings, as well as 248,000 people treated in a Pennsylvania hospital system. The findings suggested that proton pump inhibitors might increase the risk of chronic kidney disease by as much as 50%.
In April 2016, research that appeared in the Journal of the American Society of Nephrology reported that long-term users of proton pump inhibitors may be 96% more likely to develop kidney failure and 28% more likely to develop chronic kidney disease compared to patients using H2-blockers, a class of acid reducing medications that includes Zantac and Tagamet. The study, which compared 73,321 proton pump inhibitor uses to a group of 20,270 H2-blocker patients, also indicated that risk increased the longer the medications were taken.
As noted by Nexium, Prilosec and Prevacid lawsuit TV commercials, users of proton pump inhibitors may be entitled to financial compensation if they were diagnosed with serious kidney injuries, including renal failure and chronic kidney disease. To learn if you might be eligible to take legal action against a proton pump inhibitor manufacturer, please call to contact an attorney at Bernstein Liebhard LLP today.